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代谢疾病Design and synthesis of novel tricyclic benzoxazines as potent 5-HT(1A/B/D) receptor antagonists leading to the discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045).

期刊：Journal of medicinal chemistry发表年份：2010作者：Steven M Bromidge; Roberto Arban; Barbara Bertani; Silvia Bison; Manuela Borriello; Paolo Cavanni; Giovanna Dal Forno; Romano Di-Fabio; Daniele Donati; Stefano Fontana; Massimo Gianotti; Laurie J Gordon; Enrica Granci; Colin P Leslie; Luca Moccia; Al
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代谢疾病Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal transduction.

期刊：American journal of physiology. Cell physiology发表年份：2010作者：Yongping Chai; Yu-Fung Lin
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代谢疾病The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relations

期刊：Journal of medicinal chemistry发表年份：2010作者：Siew Lee Cheong; Anna Dolzhenko; Sonja Kachler; Silvia Paoletta; Stephanie Federico; Barbara Cacciari; Anton Dolzhenko; Karl-Norbert Klotz; Stefano Moro; Giampiero Spalluto; Giorgia Pastorin
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代谢疾病The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.

期刊：Journal of medicinal chemistry发表年份：2010作者：Wayne E Childers; Lisa M Havran; Magda Asselin; James J Bicksler; Dan C Chong; George T Grosu; Zhongqi Shen; Magid A Abou-Gharbia; Alvin C Bach; Boyd L Harrison; Natasha Kagan; Teresa Kleintop; Ronald Magolda; Vasilios Marathias; Albert J Robichaud;
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