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基因编辑仓鼠4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans.

期刊:Nucleic acids research发表年份:2020作者:Robert A Gaultney; Antony T Vincent; Céline Lorioux; Jean-Yves Coppée; Odile Sismeiro; Hugo Varet; Rachel Legendre; Charlotte A Cockram; Frédéric J Veyrier; Mathieu Picardeau

基因编辑仓鼠Accumulation of sphingomyelin in Niemann-Pick disease type C cells disrupts Rab9-dependent vesicular trafficking of cholesterol.

期刊:Journal of cellular physiology发表年份:2020作者:Masahiro Wanikawa; Hiroyuki Nakamura; Shunsuke Emori; Naohiro Hashimoto; Toshihiko Murayama

基因编辑仓鼠Bone morphogenetic protein 1 cleaves the linker region between ligand-binding repeats 4 and 5 of the LDL receptor and makes the LDL receptor non-functional.

期刊:Human molecular genetics发表年份:2020作者:Thea Bismo Strøm; Katrine Bjune; Trond P Leren

基因编辑仓鼠Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells.

期刊:Cellular and molecular life sciences : CMLS发表年份:2020作者:Elsa Meneses-Salas; Ana García-Melero; Kristiina Kanerva; Patricia Blanco-Muñoz; Frederic Morales-Paytuvi; Júlia Bonjoch; Josefina Casas; Antonia Egert; Syed S Beevi; Jaimy Jose; Vicenta Llorente-Cortés; Kerry-Anne Rye; Joerg Heeren; Albert Lu; Alber