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基因编辑仓鼠Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2.

期刊:British journal of pharmacology发表年份:2015作者:A Farinha; H Lavreysen; L Peeters; B Russo; S Masure; A A Trabanco; J Cid; G Tresadern

基因编辑仓鼠Development of a phenotypic high-content assay to identify pharmacoperone drugs for the treatment of primary hyperoxaluria type 1 by high-throughput screening.

期刊:Assay and drug development technologies发表年份:2015作者:Franck Madoux; Jo Ann Janovick; David Smithson; Sonia Fargue; Christopher J Danpure; Louis Scampavia; Yih-Tai Chen; Timothy P Spicer; P Michael Conn

基因编辑仓鼠NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF-06463922.

期刊:Oncotarget发表年份:2015作者:Luca Mologni; Monica Ceccon; Alessandra Pirola; Gianpaolo Chiriano; Rocco Piazza; Leonardo Scapozza; Carlo Gambacorti-Passerini

基因编辑仓鼠A novel human mutation in the SLC9A1 gene results in abolition of Na+/H+ exchanger activity.

期刊:PloS one发表年份:2015作者:Xiuju Li; Larry Fliegel