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基因编辑仓鼠A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.

期刊:PloS one发表年份:2013作者:Chiori Yabuki; Hidetoshi Komatsu; Yoshiyuki Tsujihata; Risa Maeda; Ryo Ito; Kae Matsuda-Nagasumi; Kensuke Sakuma; Kazumasa Miyawaki; Naoya Kikuchi; Koji Takeuchi; Yugo Habata; Masaaki Mori

基因编辑仓鼠Identification of determinants required for agonistic and inverse agonistic ligand properties at the ADP receptor P2Y12.

期刊:Molecular pharmacology发表年份:2013作者:Philipp Schmidt; Lars Ritscher; Elizabeth N Dong; Thomas Hermsdorf; Maxi Cöster; Doreen Wittkopf; Jens Meiler; Torsten Schöneberg

基因编辑仓鼠GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.

期刊:Molecular endocrinology (Baltimore, Md.)发表年份:2013作者:Anne-Laure Schang; Anne Granger; Bruno Quérat; Christian Bleux; Joëlle Cohen-Tannoudji; Jean-Noël Laverrière

基因编辑仓鼠Crystal structure and enzymatic activity of an ADAMTS-13 mutant with the East Asian-specific P475S polymorphism.

期刊:Journal of thrombosis and haemostasis : JTH发表年份:2013作者:M Akiyama; D Nakayama; S Takeda; K Kokame; J Takagi; T Miyata