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基因编辑仓鼠Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.

期刊:Biochemistry发表年份:2009作者:Alessandro Pandini; Anatoly A Soshilov; Yujuan Song; Jing Zhao; Laura Bonati; Michael S Denison

基因编辑仓鼠Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype.

期刊:Journal of cardiovascular electrophysiology发表年份:2009作者:Jing Ting Zhao; Adam P Hill; Anthony Varghese; Antony A Cooper; Heikki Swan; Päivi J Laitinen-Forsblom; Mark I Rees; Jonathan R Skinner; Terence J Campbell; Jamie I Vandenberg

基因编辑仓鼠The roles of selected arginine and lysine residues of TAFI (Pro-CPU) in its activation to TAFIa by the thrombin-thrombomodulin complex.

期刊:The Journal of biological chemistry发表年份:2009作者:Chengliang Wu; Paul Y Kim; Reg Manuel; Marian Seto; Marc Whitlow; Mariko Nagashima; John Morser; Ann Gils; Paul Declerck; Michael E Nesheim

基因编辑仓鼠Mutations at the signature sequence of CFTR create a Cd(2+)-gated chloride channel.

期刊:The Journal of general physiology发表年份:2009作者:Xiaohui Wang; Silvia G Bompadre; Min Li; Tzyh-Chang Hwang