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基因编辑仓鼠Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2009作者:Robert L Martone; Hua Zhou; Kevin Atchison; Thomas Comery; Jane Z Xu; Xinyi Huang; Xioahai Gong; Mei Jin; Anthony Kreft; Boyd Harrison; Scott C Mayer; Suzan Aschmies; Cathleen Gonzales; Margaret M Zaleska; David R Riddell; Erik Wagner; Peimin Lu; Sha

基因编辑仓鼠Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.

期刊:Molecular pharmacology发表年份:2009作者:Joy E Marlo; Colleen M Niswender; Emily L Days; Thomas M Bridges; Yun Xiang; Alice L Rodriguez; Jana K Shirey; Ashley E Brady; Tasha Nalywajko; Qingwei Luo; Cheryl A Austin; Michael Baxter Williams; Kwangho Kim; Richard Williams; Darren Orton; H Alex

基因编辑仓鼠Poxvirus host range protein CP77 contains an F-box-like domain that is necessary to suppress NF-kappaB activation by tumor necrosis factor alpha but is independent of its host range function.

期刊:Journal of virology发表年份:2009作者:Shu-Jung Chang; Jye-Chian Hsiao; Stephanie Sonnberg; Cheng-Ting Chiang; Min-Hsiang Yang; Der-Lii Tzou; Andrew A Mercer; Wen Chang

基因编辑仓鼠Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response.

期刊:Gastroenterology发表年份:2009作者:Li Tang; Juntao Yang; Wanli Liu; Xiaoming Tang; Jie Chen; Dianyuan Zhao; Min Wang; Feng Xu; Yantao Lu; Biao Liu; Qihong Sun; Lingqiang Zhang; Fuchu He