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代谢疾病Disadvantaged induction of gene mutations by lower chlorinated biphenyls in V79-derived cells co-expressing mouse relative to human CYP2E1, molecular docking/dynamics studies suggesting unfavored metabolic activation by the mouse enzyme.

期刊:Ecotoxicology and environmental safety发表年份:2025作者:Yuyi Luo; Keqi Hu; Hongwei Tu; Ke Xu; Shunda Zhu; Lin Wang; Yungang Liu

代谢疾病Reverse translational approach to clarify the strong potency of enavogliflozin, a novel sodium-glucose cotransporter 2 inhibitor.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2025作者:Sun-Hwa Park; Hye-Young Ji; Ji-Soo Choi; Kyung Seok Oh; Jihoon Lee; Minyeong Pang; Im-Sook Song; Joon Seok Park

代谢疾病Bioprocess biomarker identification and diagnosis for industrial mAb production based on metabolic profiling and multivariate data analysis.

期刊:Bioprocess and biosystems engineering发表年份:2025作者:Yingting Shi; Yuxiang Wan; Jiayu Yang; Yuting Lu; Xinyuan Xie; Jianyang Pan; Haibin Wang; Haibin Qu

代谢疾病Discovery and Evaluation of DA-302168S as an Efficacious Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist.

期刊:Journal of medicinal chemistry发表年份:2025作者:Guangxin Dong; Qijun Ye; Wenwen Li; Shaofeng Zhang; Zhenyu Yang; Rui Zhang; Ta Deng; Haiyan Li; Yong Zhang; Xiaojie Zhang; Shucheng He; Daoheng Zhou; Juan Zhang; Peng He; Zhou Yu; Yi Li