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代谢疾病CPL207280, a Novel G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1-Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals.

期刊：Molecular pharmacology发表年份：2021作者：Katarzyna Bazydlo-Guzenda; Pawel Buda; Mikolaj Matloka; Mateusz Mach; Filip Stelmach; Radoslaw Dzida; Damian Smuga; Joanna Hucz-Kalitowska; Malgorzata Teska-Kaminska; Varvara Vialichka; Krzysztof Dubiel; Bozena Kaminska; Maciej Wieczorek; Jerzy Piecz
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代谢疾病Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog.

期刊：Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie发表年份：2021作者：Magali Chartier; Michael Desgagné; Marc Sousbie; Charles Rumsby; Lucie Chevillard; Léa Théroux; Lounès Haroune; Jérôme Côté; Jean-Michel Longpré; Pierre-Luc Boudreault; Éric Marsault; Philippe Sarret
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代谢疾病Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease.

期刊：Scientific reports发表年份：2021作者：Sergei Pechenov; Jefferson Revell; Sarah Will; Jacqueline Naylor; Puneet Tyagi; Chandresh Patel; Lihuan Liang; Leo Tseng; Yue Huang; Anton I Rosenbaum; Kemal Balic; Anish Konkar; Joseph Grimsby; J Anand Subramony
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代谢疾病Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.

期刊：Bioorganic & medicinal chemistry发表年份：2021作者：Masahiro Kamaura; Osamu Kubo; Hiromichi Sugimoto; Naoyoshi Noguchi; Hirohisa Miyashita; Shinichi Abe; Kae Matsuda; Yoshiyuki Tsujihata; Tomoyuki Odani; Shinji Iwasaki; Toshiki Murata; Kenjiro Sato
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