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代谢疾病Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

期刊:The Journal of biological chemistry发表年份:2017作者:Pauline Bonvin; Franck Gueneau; Vanessa Buatois; Maud Charreton-Galby; Stanley Lasch; Marie Messmer; Urs Christen; Andrew D Luster; Zoë Johnson; Walter Ferlin; Marie Kosco-Vilbois; Amanda Proudfoot; Nicolas Fischer

代谢疾病Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5.

期刊:Endocrinology发表年份:2017作者:Thomas B Farb; Marta Adeva; Thomas J Beauchamp; Over Cabrera; David A Coates; Tamika DeShea Meredith; Brian A Droz; Alexander Efanov; James V Ficorilli; Susan L Gackenheimer; Maria A Martinez-Grau; Victoriano Molero; Gema Ruano; Michael A Statnick; T

代谢疾病Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analog.

期刊:American journal of physiology. Endocrinology and metabolism发表年份:2017作者:Sofie Gydesen; Kim Vietz Andreassen; Sara Toftegaard Hjuler; Lars I Hellgren; Morten Asser Karsdal; Kim Henriksen

代谢疾病Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals.

期刊:mAbs发表年份:2017作者:Sharmila Rajan; Danielle Mandikian; Amos Baruch; Thomas R Gelzleichter; Dale Stevens; Junichiro Sonoda; Kyra Cowan; C Andrew Boswell; Eric Stefanich