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代谢疾病G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism.

期刊：The Journal of pharmacology and experimental therapeutics发表年份：2014作者：Ryan M Fryer; Khing Jow Ng; Suzanne G Nodop Mazurek; Lori Patnaude; Donna J Skow; Akalushi Muthukumarana; Kyle E Gilpin; Roger M Dinallo; Daniel Kuzmich; John Lord; Sulagna Sanyal; Hui Yu; Christian Harcken; Matthew A Cerny; Eugene R Hickey; Louise K
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代谢疾病Improved glucose metabolism in vitro and in vivo by an allosteric monoclonal antibody that increases insulin receptor binding affinity.

期刊：PloS one发表年份：2014作者：John A Corbin; Vinay Bhaskar; Ira D Goldfine; Daniel H Bedinger; Angela Lau; Kristen Michelson; Lisa M Gross; Betty A Maddux; Hua F Kuan; Catarina Tran; Llewelyn Lao; Masahisa Handa; Susan R Watson; Ajay J Narasimha; Shirley Zhu; Raphael Levy; Lynn W
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代谢疾病A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.

期刊：BMC pharmacology & toxicology发表年份：2014作者：Tharappel M Anil; Anilkumar Dandu; KrishnaReddy Harsha; Jaideep Singh; Nitya Shree; Venkatesh Satish Kumar; Mudigere N Lakshmi; Venkategowda Sunil; Chandrashekaran Harish; Gundalmandikal V Balamurali; Baisani S Naveen Kumar; Aralakuppe S Gopala; Shiv
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代谢疾病Enhanced cholesterol efflux to HDL through the ABCA1 transporter in hypertriglyceridemia of type 2 diabetes.

期刊：Metabolism: clinical and experimental发表年份：2014作者：Hussein N Yassine; Alexandra Belopolskaya; Christina Schall; Craig S Stump; Serrine S Lau; Peter D Reaven
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