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代谢疾病Nonclinical toxicology assessments support the chronic safety of dapagliflozin, a first-in-class sodium-glucose cotransporter 2 inhibitor.

期刊：International journal of toxicology发表年份：2013作者：Mark Tirmenstein; Thomas E Dorr; Evan B Janovitz; Deborah Hagan; Lynn M Abell; Joelle M Onorato; Jean M Whaley; Michael J Graziano; Timothy P Reilly
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代谢疾病Scaffold hopping approach towards various AFQ-056 analogs as potent metabotropic glutamate receptor 5 negative allosteric modulators.

期刊：Bioorganic & medicinal chemistry letters发表年份：2013作者：Holger Kubas; Udo Meyer; Mirko Hechenberger; Kai-Uwe Klein; Patrick Plitt; Ronalds Zemribo; Harm W Spexgoor; Sander G A van Assema; Ulrich Abel
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代谢疾病Partial agonist efficacy of EMD386088, a 5-HT6 receptor ligand, in functional in vitro assays.

期刊：Pharmacological reports : PR发表年份：2013作者：Magdalena Jastrzębska-Więsek; Agata Siwek; Grzegorz Kazek; Barbara Nawieśniak; Anna Partyka; Monika Marcinkowska; Marcin Kołaczkowski; Anna Wesołowska
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代谢疾病6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.

期刊：Journal of medicinal chemistry发表年份：2013作者：Stephan Röver; Mirjana Andjelkovic; Agnès Bénardeau; Evelyne Chaput; Wolfgang Guba; Paul Hebeisen; Susanne Mohr; Matthias Nettekoven; Ulrike Obst; Wolfgang F Richter; Christoph Ullmer; Pius Waldmeier; Matthew B Wright
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