郑州微飒生物科技有限责任公司 咨询热线：0371-88821766
行业动态

行业动态

追踪行业前沿，洞察产业趋势

代谢疾病Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists.

期刊：Journal of medicinal chemistry发表年份：2011作者：Mario van der Stelt; Jos Cals; Silvia Broeders-Josten; Jean Cottney; Antoon A van der Doelen; Marcel Hermkens; Vera de Kimpe; Angela King; Jan Klomp; Julia Oosterom; Ilse Pols-de Rooij; Jeroen de Roos; Martin van Tilborg; Susan Boyce; James Baker
阅读更多 →

代谢疾病Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives.

期刊：Journal of medicinal chemistry发表年份：2011作者：Masato Yoshida; Akira Mori; Etsuo Kotani; Masahiro Oka; Haruhiko Makino; Hisashi Fujita; Junko Ban; Yukihiro Ikeda; Tomohiro Kawamoto; Mika Goto; Hiroyuki Kimura; Atsuo Baba; Tsuneo Yasuma
阅读更多 →

代谢疾病Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.

期刊：Journal of medicinal chemistry发表年份：2011作者：Chun-Hsu Yao; Jen-Shin Song; Chiung-Tong Chen; Teng-Kuang Yeh; Ming-Shiu Hung; Chih-Chun Chang; Yu-Wei Liu; Mao-Chia Yuan; Chieh-Jui Hsieh; Chung-Yu Huang; Min-Hsien Wang; Ching-Hui Chiu; Tsung-Chih Hsieh; Szu-Huei Wu; Wen-Chi Hsiao; Kuang-Feng Chu;
阅读更多 →

代谢疾病Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.

期刊：American journal of physiology. Endocrinology and metabolism发表年份：2011作者：Stephen V Straub; Sylvie M Perez; Beijing Tan; Kimberly A Coughlan; Catherine E Trebino; Patricia Cosgrove; Joanne M Buxton; John M Kreeger; V Margaret Jackson
阅读更多 →