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心血管疾病Target-seeking antifibrotic compound enhances wound healing and suppresses scar formation in mice.

期刊:Proceedings of the National Academy of Sciences of the United States of America发表年份:2010作者:Tero A H Järvinen; Erkki Ruoslahti

心血管疾病Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.

期刊:The Journal of clinical investigation发表年份:2010作者:Hitoshi Takizawa; Satoshi Nishimura; Naoya Takayama; Atsushi Oda; Hidekazu Nishikii; Yohei Morita; Sei Kakinuma; Satoshi Yamazaki; Satoshi Okamura; Noriko Tamura; Shinya Goto; Akira Sawaguchi; Ichiro Manabe; Kiyoshi Takatsu; Hiromitsu Nakauchi; Satos

心血管疾病Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).

期刊:Journal of medicinal chemistry发表年份:2010作者:Luc Roumen; Joris W Peeters; Judith M A Emmen; Ilona P E Beugels; Erica M G Custers; Marcel de Gooyer; Ralf Plate; Koen Pieterse; Peter A J Hilbers; Jos F M Smits; Jef A J Vekemans; Dirk Leysen; Harry C J Ottenheijm; Henk M Janssen; J J Rob Hermans

心血管疾病Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin.

期刊:Biochemistry发表年份:2010作者:Matthew W Parker; Lance M Hellman; Ping Xu; Michael G Fried; Craig W Vander Kooi