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心血管疾病Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.

期刊:ACS chemical biology发表年份:2008作者:Stephan C Schürer; Steven J Brown; Pedro J Gonzalez-Cabrera; Marie-Therese Schaeffer; Jacqueline Chapman; Euijung Jo; Peter Chase; Tim Spicer; Peter Hodder; Hugh Rosen

心血管疾病Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

期刊:Pflugers Archiv : European journal of physiology发表年份:2008作者:Anders Peter Larsen; Søren-Peter Olesen; Morten Grunnet; Thomas Jespersen

心血管疾病A high-throughput screen for endothelial lipase using HDL as substrate.

期刊:Journal of biomolecular screening发表年份:2008作者:Paul M Keller; Timothy Rust; Dennis J Murphy; Rosalie Matico; John J Trill; John A Krawiec; Anthony Jurewicz; Michael Jaye; Mark Harpel; Sara Thrall; Benjamin Schwartz

心血管疾病Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase.

期刊:Journal of lipid research发表年份:2008作者:Anne P Beigneux; Peter Gin; Brandon S J Davies; Michael M Weinstein; André Bensadoun; Robert O Ryan; Loren G Fong; Stephen G Young