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心血管疾病A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its acti

期刊：The Journal of pharmacology and experimental therapeutics发表年份：2008作者：Keiichi Kuwano; Asami Hashino; Kumiko Noda; Keiji Kosugi; Kenji Kuwabara
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心血管疾病Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension.

期刊：Bioorganic & medicinal chemistry发表年份：2008作者：Osamu Ohno; Mao Ye; Tomoyuki Koyama; Kazunaga Yazawa; Emi Mura; Hiroshi Matsumoto; Takao Ichino; Kaoru Yamada; Kazuhiko Nakamura; Tomohiro Ohno; Kohji Yamaguchi; Junji Ishida; Akiyoshi Fukamizu; Daisuke Uemura
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心血管疾病Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.

期刊：Journal of cardiovascular pharmacology发表年份：2008作者：Young Jin Kim; Hee Kyung Hong; Hui Sun Lee; Sang Hyun Moh; Jong Cook Park; Su Hyun Jo; Han Choe
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心血管疾病Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of

期刊：Journal of medicinal chemistry发表年份：2008作者：Jeffrey A Pfefferkorn; Chulho Choi; Scott D Larsen; Bruce Auerbach; Richard Hutchings; William Park; Valerie Askew; Lisa Dillon; Jeffrey C Hanselman; Zhiwu Lin; Gina H Lu; Andrew Robertson; Catherine Sekerke; Melissa S Harris; Alexander Pavlovsky; Gr
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