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代谢疾病3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs.

期刊:Bioorganic & medicinal chemistry发表年份:2010作者:Masaki Asada; Tetsuo Obitsu; Atsushi Kinoshita; Toshihiko Nagase; Tadahiro Yoshida; Yoshiyuki Yamaura; Hiroya Takizawa; Ken Yoshikawa; Kazutoyo Sato; Masami Narita; Hisao Nakai; Masaaki Toda; Yoshito Tobe

代谢疾病Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

期刊:Journal of medicinal chemistry发表年份:2010作者:Giovanni Abbenante; Bernd Becker; Sébastien Blanc; Chris Clark; Glenn Condie; Graeme Fraser; Matthias Grathwohl; Judy Halliday; Senka Henderson; Ann Lam; Ligong Liu; Maretta Mann; Craig Muldoon; Andrew Pearson; Rajaratnam Premraj; Tracie Ramsdale; To

代谢疾病Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.

期刊:Journal of medicinal chemistry发表年份:2010作者:Cédric Genet; Axelle Strehle; Céline Schmidt; Geoffrey Boudjelal; Annelise Lobstein; Kristina Schoonjans; Michel Souchet; Johan Auwerx; Régis Saladin; Alain Wagner

代谢疾病Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs.

期刊:Peptides发表年份:2010作者:Tasir S Haque; Ving G Lee; Douglas Riexinger; Ming Lei; Sarah Malmstrom; Li Xin; Songping Han; Claudio Mapelli; Christopher B Cooper; Ge Zhang; William R Ewing; John Krupinski