病毒感染Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.
期刊：Journal of medicinal chemistry发表年份：2015作者：Guangyi Wang; Jerome Deval; Jin Hong; Natalia Dyatkina; Marija Prhavc; Joshua Taylor; Amy Fung; Zhinan Jin; Sarah K Stevens; Vladimir Serebryany; Jyanwei Liu; Qingling Zhang; Yuen Tam; Sushmita M Chanda; David B Smith; Julian A Symons; Lawrence M Bla