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代谢疾病A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain.

期刊:Neuroendocrinology发表年份:2005作者:Heather A Halem; John E Taylor; Jesse Z Dong; Yeelana Shen; Rakesh Datta; Alfonso Abizaid; Sabrina Diano; Tamas L Horvath; Michael D Culler

代谢疾病Degradation, insulin secretion, and antihyperglycemic actions of two palmitate-derivitized N-terminal pyroglutamyl analogues of glucose-dependent insulinotropic polypeptide.

期刊:Journal of medicinal chemistry发表年份:2005作者:Nigel Irwin; Brian D Green; Victor A Gault; Brett Greer; Patrick Harriott; Clifford J Bailey; Peter R Flatt; Finbarr P M O'Harte

代谢疾病Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.

期刊:Diabetes发表年份:2005作者:Houtan Noushmehr; Eugenio D'Amico; Loredana Farilla; Hongxiang Hui; Kolja A Wawrowsky; Wojciech Mlynarski; Alessandro Doria; Nada A Abumrad; Riccardo Perfetti

代谢疾病Development and application of a scintillation proximity assay (SPA) for identification of selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

期刊:Assay and drug development technologies发表年份:2005作者:S Mundt; K Solly; R Thieringer; A Hermanowski-Vosatka