行业动态 - 郑州微飒生物科技有限责任公司

代谢疾病Genetic-induced variations in the GAD65 T-cell repertoire governs efficacy of anti-CD3/GAD65 combination therapy in new-onset type 1 diabetes.

期刊：Molecular therapy : the journal of the American Society of Gene Therapy发表年份：2010作者：Damien Bresson; Matthew Fradkin; Yulia Manenkova; Diane Rottembourg; Matthias von Herrath

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代谢疾病Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

期刊：Molecular pharmacology发表年份：2010作者：Cassandra Koole; Denise Wootten; John Simms; Celine Valant; Rohan Sridhar; Owen L Woodman; Laurence J Miller; Roger J Summers; Arthur Christopoulos; Patrick M Sexton

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代谢疾病(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.

期刊：Journal of medicinal chemistry发表年份：2010作者：Hiroyuki Kakinuma; Takahiro Oi; Yuko Hashimoto-Tsuchiya; Masayuki Arai; Yasunori Kawakita; Yoshiki Fukasawa; Izumi Iida; Naoko Hagima; Hiroyuki Takeuchi; Yukihiro Chino; Jun Asami; Lisa Okumura-Kitajima; Fusayo Io; Daisuke Yamamoto; Noriyuki Miyata;

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代谢疾病Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.

期刊：PloS one发表年份：2010作者：Malcolm A Leissring; Enrico Malito; Sabrine Hedouin; Lael Reinstatler; Tomoko Sahara; Samer O Abdul-Hay; Shakeel Choudhry; Ghulam M Maharvi; Abdul H Fauq; Malwina Huzarska; Philip S May; Sungwoon Choi; Todd P Logan; Benjamin E Turk; Lewis C Cantley;

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