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基因编辑仓鼠Insertion in the N-Terminal Domain of the SARS-CoV-2 Spike Glycoprotein Affects Antibody Recognition and Phenotypic Properties.

期刊:Viruses发表年份:2026作者:Elena A Ermolaeva; Anna N Zyrina; Dina I Sirazova; Alexander S Lunin; Anton S Motov; Anastasia D Chernavtseva; Olga S Gancharova; Liubov I Kozlovskaya; Anna A Shishova; Alexandra A Siniugina; Aydar A Ishmukhametov

基因编辑仓鼠CRISPR-based mutagenesis of lipopolysaccharide biosynthesis genes in Leptospira interrogans reveals gene essentiality and confirms the role of an O-antigen polymerase.

期刊:Scientific reports发表年份:2026作者:Luis G V Fernandes; Jarlath E Nally

基因编辑仓鼠Ames concordance with the in vivo transgenic rodent (TGR) gene mutation assay for NDSRIs and relative in vivo TGR potency with nitrosamines with robust dose-response carcinogenicity data.

期刊:Regulatory toxicology and pharmacology : RTP发表年份:2026作者:Robert A Jolly; Alejandra Trejo-Martin; Joel P Bercu; Mark W Powley; Rachael E Tennant; David J Ponting; Raphael Nudelman; Zhanna Sobol; Andreas Czich; George E Johnson; Yi Yang; Tetyana Kobets; Paul A White; Sheroy Minocherhomji; Anthony M Lynch; An

基因编辑仓鼠SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS-STING.

期刊:The Journal of general virology发表年份:2026作者:Hsin-Ping Chiu; Yao Yu Yeo; Tsoi Ying Lai; Chuan-Tien Hung; Shreyas Kowdle; Griffin D Haas; Sizun Jiang; Weina Sun; Benhur Lee