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药效评价Investigating the Influence of Tracer Kinetics on Competition-Kinetic Association Binding Assays: Identifying the Optimal Conditions for Assessing the Kinetics of Low-Affinity Compounds.

期刊:Molecular pharmacology发表年份:2019作者:David A Sykes; Palash Jain; Steven J Charlton

药效评价Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor.

期刊:Journal of medicinal chemistry发表年份:2019作者:Tim J Fyfe; Barrie Kellam; David A Sykes; Ben Capuano; Peter J Scammells; J Robert Lane; Steven J Charlton; Shailesh N Mistry

药效评价Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles.

期刊:Chemical communications (Cambridge, England)发表年份:2019作者:Chahat Mehra; Ravisha Gala; Aarti Kakatkar; Vivekanand Kumar; Raman Khurana; Suchandra Chatterjee; N Naveen Kumar; Nilotpal Barooah; Achikanath C Bhasikuttan; Jyotirmayee Mohanty

药效评价Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3'-fluoro-4'-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder.

期刊:European journal of pharmacology发表年份:2019作者:Yi Zheng; Samuel Obeng; Bethany A Reinecke; Chongguang Chen; Palak S Phansalkar; David M Walentiny; Phillip M Gerk; Lee-Yuan Liu-Chen; Dana E Selley; Patrick M Beardsley; Yan Zhang