心血管疾病Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of
期刊:Journal of medicinal chemistry发表年份:2008作者:Jeffrey A Pfefferkorn; Chulho Choi; Scott D Larsen; Bruce Auerbach; Richard Hutchings; William Park; Valerie Askew; Lisa Dillon; Jeffrey C Hanselman; Zhiwu Lin; Gina H Lu; Andrew Robertson; Catherine Sekerke; Melissa S Harris; Alexander Pavlovsky; Gr