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心血管疾病Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.

期刊:Journal of cardiovascular pharmacology发表年份:2008作者:Young Jin Kim; Hee Kyung Hong; Hui Sun Lee; Sang Hyun Moh; Jong Cook Park; Su Hyun Jo; Han Choe

心血管疾病Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of

期刊:Journal of medicinal chemistry发表年份:2008作者:Jeffrey A Pfefferkorn; Chulho Choi; Scott D Larsen; Bruce Auerbach; Richard Hutchings; William Park; Valerie Askew; Lisa Dillon; Jeffrey C Hanselman; Zhiwu Lin; Gina H Lu; Andrew Robertson; Catherine Sekerke; Melissa S Harris; Alexander Pavlovsky; Gr

心血管疾病Update of the Pompe disease mutation database with 107 sequence variants and a format for severity rating.

期刊:Human mutation发表年份:2008作者:Marian Kroos; Robert J Pomponio; Laura van Vliet; Rachel E Palmer; Michael Phipps; Robert Van der Helm; Dicky Halley; Arnold Reuser; GAA Database Consortium

心血管疾病Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance.

期刊:Circulation research发表年份:2008作者:Nazish Sayed; David D Kim; Xavier Fioramonti; Toru Iwahashi; Walter N Durán; Annie Beuve