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药效评价1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor.

期刊：Journal of medicinal chemistry发表年份：2018作者：Fabio Del Bello; Alessandro Bonifazi; Gianfabio Giorgioni; Carlo Cifani; Maria Vittoria Micioni Di Bonaventura; Riccardo Petrelli; Alessandro Piergentili; Stefano Fontana; Valerio Mammoli; Hideaki Yano; Rosanna Matucci; Giulio Vistoli; Wilma Quaglia
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药效评价A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.

期刊：Nature chemical biology发表年份：2018作者：Aaron H Nile; Felipe de Sousa E Melo; Susmith Mukund; Robert Piskol; Simon Hansen; Lijuan Zhou; Yingnan Zhang; Yue Fu; Emily B Gogol; László G Kömüves; Zora Modrusan; Stephane Angers; Yvonne Franke; Christopher Koth; Wayne J Fairbrother; Weiru Wang;
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药效评价A novel nanoparticle delivery system for targeted therapy of noise-induced hearing loss.

期刊：Journal of controlled release : official journal of the Controlled Release Society发表年份：2018作者：Mohammad N Kayyali; Julian R A Wooltorton; Andrew J Ramsey; Mei Lin; Tiffany N Chao; Andrew Tsourkas; Bert W O'Malley; Daqing Li
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药效评价The Temperature Dependence of Kinetics Associated with Drug Block of hERG Channels Is Compound-Specific and an Important Factor for Proarrhythmic Risk Prediction.

期刊：Molecular pharmacology发表年份：2018作者：Monique J Windley; William Lee; Jamie I Vandenberg; Adam P Hill
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