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药效评价Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis.

期刊:British journal of pharmacology发表年份:2017作者:Mark Barbour; Melissa McNaughton; Stephanie D Boomkamp; Neil MacRitchie; Hui-Rong Jiang; Nigel J Pyne; Susan Pyne

药效评价Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.

期刊:Scientific reports发表年份:2017作者:Ralph Adams; Rebecca J Burnley; Chiara R Valenzano; Omar Qureshi; Carl Doyle; Simon Lumb; Maria Del Carmen Lopez; Robert Griffin; David McMillan; Richard D Taylor; Chris Meier; Prashant Mori; Laura M Griffin; Ulrich Wernery; Jörg Kinne; Stephen Rapec

药效评价Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers.

期刊:The Journal of biological chemistry发表年份:2017作者:Imane Moutkine; Emily Quentin; Bruno P Guiard; Luc Maroteaux; Stephane Doly

药效评价Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents.

期刊:Future medicinal chemistry发表年份:2017作者:Rob De Vreese; Carmen de Kock; Peter J Smith; Kelly Chibale; Matthias D'hooghe