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药效评价BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor.

期刊：Neuropharmacology发表年份：2017作者：Konstantinos Botsakis; Theodora Mourtzi; Vasiliki Panagiotakopoulou; Malamati Vreka; Georgios T Stathopoulos; Iosif Pediaditakis; Ioannis Charalampopoulos; Achilleas Gravanis; Foteini Delis; Katerina Antoniou; Dimitrios Zisimopoulos; Christos D Georg
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药效评价Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.

期刊：The Journal of biological chemistry发表年份：2017作者：Feng Ye; Chansik Yang; Jiyoon Kim; Christopher J MacNevin; Klaus M Hahn; Dongeun Park; Mark H Ginsberg; Chungho Kim
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药效评价Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.

期刊：British journal of pharmacology发表年份：2017作者：Mariana Spetea; Shainnel O Eans; Michelle L Ganno; Aquilino Lantero; Michael Mairegger; Lawrence Toll; Helmut Schmidhammer; Jay P McLaughlin
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药效评价Ligand chain length drives activation of lipid G protein-coupled receptors.

期刊：Scientific reports发表年份：2017作者：Anastassia Troupiotis-Tsaïlaki; Julian Zachmann; Inés González-Gil; Angel Gonzalez; Silvia Ortega-Gutiérrez; Maria L López-Rodríguez; Leonardo Pardo; Cedric Govaerts
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