郑州微飒生物科技有限责任公司 咨询热线：0371-88821766
行业动态

行业动态

追踪行业前沿，洞察产业趋势

药效评价A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators.

期刊：Molecular pharmacology发表年份：2006作者：Kamondanai Hemstapat; Tomas de Paulis; Yelin Chen; Ashley E Brady; Vandana K Grover; David Alagille; Gilles D Tamagnan; P Jeffrey Conn
阅读更多 →

药效评价Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling.

期刊：Molecular pharmacology发表年份：2006作者：Peter J Atkinson; Kenneth W Young; Steven J Ennion; James N C Kew; Stefan R Nahorski; R A John Challiss
阅读更多 →

药效评价Novel benzodiazepine photoaffinity probe stereoselectively labels a site deep within the membrane-spanning domain of the cholecystokinin receptor.

期刊：Journal of medicinal chemistry发表年份：2006作者：Elizabeth M Hadac; Eric S Dawson; James W Darrow; Elizabeth E Sugg; Terry P Lybrand; Laurence J Miller
阅读更多 →

药效评价Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.

期刊：The Journal of pharmacology and experimental therapeutics发表年份：2006作者：Ruggero Galici; Carrie K Jones; Kamondanai Hemstapat; Yi Nong; Nicholas G Echemendia; Lilly C Williams; Tomas de Paulis; P Jeffrey Conn
阅读更多 →