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药效评价Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).

期刊:Journal of medicinal chemistry发表年份:2016作者:Pushkar M Kulkarni; Abhijit R Kulkarni; Anisha Korde; Ritesh B Tichkule; Robert B Laprairie; Eileen M Denovan-Wright; Han Zhou; David R Janero; Nikolai Zvonok; Alexandros Makriyannis; Maria G Cascio; Roger G Pertwee; Ganesh A Thakur

药效评价Positive Allosteric Modulation of the Muscarinic M1 Receptor Improves Efficacy of Antipsychotics in Mouse Glutamatergic Deficit Models of Behavior.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2016作者:Kwok H C Choy; David M Shackleford; Daniel T Malone; Shailesh N Mistry; Rahul T Patil; Peter J Scammells; Christopher J Langmead; Christos Pantelis; Patrick M Sexton; Johnathan R Lane; Arthur Christopoulos

药效评价Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

期刊:Journal of medicinal chemistry发表年份:2016作者:Scott D Edmondson; Cheng Zhu; Nam Fung Kar; Jerry Di Salvo; Hiroshi Nagabukuro; Beatrice Sacre-Salem; Karen Dingley; Richard Berger; Stephen D Goble; Gregori Morriello; Bart Harper; Christopher R Moyes; Dong-Ming Shen; Liping Wang; Richard Ball; Aile

药效评价A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25-35-impaired mouse cognitive function.

期刊:Psychopharmacology发表年份:2016作者:Zhengping Zhang; Rong Chen; Wenji An; Chunmei Wang; Gaoyong Liao; Xiaoliang Dong; Aijing Bi; Zhimin Yin; Lan Luo