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药效评价Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors.

期刊:Purinergic signalling发表年份:2015作者:Mohamad Wessam Alnouri; Stephan Jepards; Alessandro Casari; Anke C Schiedel; Sonja Hinz; Christa E Müller

药效评价Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays.

期刊:Biochemical pharmacology发表年份:2015作者:Milan Stoiljkovic; Liza Leventhal; Angela Chen; Ting Chen; Rachelle Driscoll; Dorothy Flood; Hilliary Hodgdon; Raymond Hurst; David Nagy; Timothy Piser; Cuyue Tang; Matthew Townsend; Zhiming Tu; Daniel Bertrand; Gerhard Koenig; Mihaly Hajós

药效评价Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport.

期刊:Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology发表年份:2015作者:Narasimha M Midde; Yaxia Yuan; Pamela M Quizon; Wei-Lun Sun; Xiaoqin Huang; Chang-Guo Zhan; Jun Zhu

药效评价Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG.

期刊:The Journal of biological chemistry发表年份:2015作者:Gregory P Owens; Alanna Ritchie; Andrea Rossi; Kristin Schaller; Scott Wemlinger; Hannah Schumann; Andrew Shearer; Alan S Verkman; Jeffrey L Bennett