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基因编辑仓鼠Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance.

期刊：Journal of virology发表年份：2014作者：Xufang Deng; Sarah E StJohn; Heather L Osswald; Amornrat O'Brien; Bridget S Banach; Katrina Sleeman; Arun K Ghosh; Andrew D Mesecar; Susan C Baker
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基因编辑仓鼠A single amino acid substitution in CFTR converts ATP to an inhibitory ligand.

期刊：The Journal of general physiology发表年份：2014作者：Wen-Ying Lin; Kang-Yang Jih; Tzyh-Chang Hwang
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基因编辑仓鼠Inhibition of ubiquitin proteasome system rescues the defective sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA1) protein causing Chianina cattle pseudomyotonia.

期刊：The Journal of biological chemistry发表年份：2014作者：Elisa Bianchini; Stefania Testoni; Arcangelo Gentile; Tito Calì; Denis Ottolini; Antonello Villa; Marisa Brini; Romeo Betto; Francesco Mascarello; Poul Nissen; Dorianna Sandonà; Roberta Sacchetto
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基因编辑仓鼠Interferon-stimulated poly(ADP-Ribose) polymerases are potent inhibitors of cellular translation and virus replication.

期刊：Journal of virology发表年份：2014作者：Svetlana Atasheva; Elena I Frolova; Ilya Frolov
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