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基因编辑仓鼠De novo mutations in HCN1 cause early infantile epileptic encephalopathy.

期刊：Nature genetics发表年份：2014作者：Caroline Nava; Carine Dalle; Agnès Rastetter; Pasquale Striano; Carolien G F de Kovel; Rima Nabbout; Claude Cancès; Dorothée Ville; Eva H Brilstra; Giuseppe Gobbi; Emmanuel Raffo; Delphine Bouteiller; Yannick Marie; Oriane Trouillard; Angela Robbiano
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基因编辑仓鼠Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage.

期刊：Cell death & disease发表年份：2014作者：S Li; J Deng; H Hou; J Tian; B Giunta; Y Wang; D Sawmiller; A Smith; P R Sanberg; D Obregon; T Mori; J Tan
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基因编辑仓鼠CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.

期刊：mAbs发表年份：2014作者：Michael D Oberst; Stacy Fuhrmann; Kathy Mulgrew; Maria Amann; Lily Cheng; Petra Lutterbuese; Laura Richman; Steve Coats; Patrick A Baeuerle; Scott A Hammond
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基因编辑仓鼠ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

期刊：The Journal of clinical investigation发表年份：2014作者：Haiyan Qiu; Sebum Lee; Yulei Shang; Wen-Yuan Wang; Kin Fai Au; Sherry Kamiya; Sami J Barmada; Steven Finkbeiner; Hansen Lui; Caitlin E Carlton; Amy A Tang; Michael C Oldham; Hejia Wang; James Shorter; Anthony J Filiano; Erik D Roberson; Warren G Tour
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