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药效评价Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor.

期刊:Molecular pharmacology发表年份:2015作者:Elham Khajehali; Daniel T Malone; Michelle Glass; Patrick M Sexton; Arthur Christopoulos; Katie Leach

药效评价A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects.

期刊:Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology发表年份:2015作者:Bogna M Ignatowska-Jankowska; Gemma L Baillie; Steven Kinsey; Molly Crowe; Sudeshna Ghosh; Robert A Owens; Imad M Damaj; Justin Poklis; Jenny L Wiley; Matteo Zanda; Chiara Zanato; Iain R Greig; Aron H Lichtman; Ruth A Ross

药效评价Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels.

期刊:Biotechnology progress发表年份:2015作者:Craig Zupke; Lowell J Brady; Peter G Slade; Philip Clark; R Guy Caspary; Brittney Livingston; Lisa Taylor; Kyle Bigham; Arvia E Morris; Robert W Bailey

药效评价Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation.

期刊:British journal of pharmacology发表年份:2015作者:Lingxin Wang; Shannon G Zellmer; David M Printzenhoff; Neil A Castle