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药效评价Development and scale-up of the recovery and purification of a domain antibody Fc fusion protein-comparison of a two and three-step approach.

期刊:Biotechnology and bioengineering发表年份:2015作者:Sibylle Herzer; Atul Bhangale; Gregory Barker; Isha Chowdhary; Matthew Conover; Brian W O'Mara; Lily Tsang; Shi-Yu Wang; Stanley R Krystek; Yan Yao; Siegfried Rieble

药效评价Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands.

期刊:Bioorganic & medicinal chemistry发表年份:2015作者:Yunyun Yuan; Saheem A Zaidi; David L Stevens; Krista L Scoggins; Philip D Mosier; Glen E Kellogg; William L Dewey; Dana E Selley; Yan Zhang

药效评价The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys.

期刊:Biological psychiatry发表年份:2015作者:Zuzana Justinova; Leigh V Panlilio; Maria E Secci; Godfrey H Redhi; Charles W Schindler; Alan J Cross; Ladislav Mrzljak; Amy Medd; Yavin Shaham; Steven R Goldberg

药效评价Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential.

期刊:Journal of medicinal chemistry发表年份:2015作者:Mario de la Fuente Revenga; Nerea Fernández-Sáez; Clara Herrera-Arozamena; José A Morales-García; Sandra Alonso-Gil; Ana Pérez-Castillo; Daniel-Henri Caignard; Silvia Rivara; María Isabel Rodríguez-Franco