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代谢疾病Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.

期刊:Nature communications发表年份:2025作者:Pengbo Liu; Dongsheng Ren; Guichang Li; Xiaoming Xu; Luca Presotto; Wei Liu; Ning Zhao; Dongmei Li; Min Chen; Jun Wang; Xiaobo Liu; Chunchun Zhao; Liang Lu; Qiyong Liu

代谢疾病HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions.

期刊:Regulatory toxicology and pharmacology : RTP发表年份:2025作者:Joel Bercu; Alejandra Trejo-Martin; Connie Chen; Maik Schuler; Jennifer Cheung; Tetyana Cheairs; Anthony M Lynch; Dean Thomas; Andreas Czich; Aisar Atrakchi; Timothy J McGovern; Robert H Heflich; Alisa Vespa; Roland Froetschl; Yi Yang; Raj D Gandhi;

代谢疾病Anti-b diminishes hyperlipidaemia and hepatic steatosis in hamsters and mice by suppressing the mTOR/PPARγ and mTOR/SREBP1 signalling pathways.

期刊:British journal of pharmacology发表年份:2025作者:Yu Bian; Han Wu; Weitao Jiang; Xue Kong; Yuting Xiong; Linghua Zeng; Feng Zhang; Jinglun Song; Chunlei Wang; Yang Yang; Xinyue Zhang; Yuning Zhang; Ping Pang; Tianqi Duo; Zhuo Wang; Tengfei Pan; Baofeng Yang

代谢疾病HTD1801 demonstrates promising potential for histologic improvements in metabolic dysfunction-associated steatohepatitis in both a preclinical and phase 2 study.

期刊:Clinical and molecular hepatology发表年份:2025作者:Vincent Wai-Sun Wong; Guy W Neff; Adrian M Di Bisceglie; Ru Bai; Junwei Cheng; Meng Yu; Alexander Liberman; Liping Liu; Nadege Gunn