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药效评价Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.

期刊:Circulation research发表年份:2014作者:Xiaowei Wang; Jathushan Palasubramaniam; Yannik Gkanatsas; Jan David Hohmann; Erik Westein; Ruchi Kanojia; Karen Alt; Dexing Huang; Fu Jia; Ingo Ahrens; Robert L Medcalf; Karlheinz Peter; Christoph E Hagemeyer

药效评价Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.

期刊:Journal of medicinal chemistry发表年份:2014作者:Dean G Brown; Peter R Bernstein; Andrew Griffin; Steve Wesolowski; Denis Labrecque; Maxime C Tremblay; Mark Sylvester; Russell Mauger; Phillip D Edwards; Scott R Throner; James J Folmer; Joseph Cacciola; Clay Scott; Lois A Lazor; Mehrnaz Pourashraf;

药效评价A biochemical and physicochemical comparison of two recombinant enzymes used for enzyme replacement therapies of hunter syndrome.

期刊:Glycoconjugate journal发表年份:2014作者:Yo Kyung Chung; Young Bae Sohn; Jong Mun Sohn; Jieun Lee; Mi Sun Chang; Younghee Kwun; Chi Hwa Kim; Jin Young Lee; Yeon Joo Yook; Ah-Ra Ko; Dong-Kyu Jin

药效评价Resibufogenin and cinobufagin activate central neurons through an ouabain-like action.

期刊:PloS one发表年份:2014作者:Ze-Jun Wang; Liqin Sun; Thomas Heinbockel