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药效评价Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists.

期刊:Bioorganic & medicinal chemistry发表年份:2014作者:Ayako Moritomo; Hiroyoshi Yamada; Takaho Matsuzawa-Nomura; Toshihiro Watanabe; Hirotsune Itahana; Makoto Oku; Shinobu Akuzawa; Minoru Okada

药效评价In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists.

期刊:Journal of medicinal chemistry发表年份:2014作者:Dilip K Tosh; Amanda Finley; Silvia Paoletta; Steven M Moss; Zhan-Guo Gao; Elizabeth T Gizewski; John A Auchampach; Daniela Salvemini; Kenneth A Jacobson

药效评价Determining the relative efficacy of positive allosteric modulators of the GABAA receptor: design of a screening approach.

期刊:Journal of biomolecular screening发表年份:2014作者:Philippe Ghisdal; Nadine Noel; Nathalie Pacico; Murielle Martini; Patrik Foerch; Etienne Hanon; Christian Wolff

药效评价The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.

期刊:The international journal of neuropsychopharmacology发表年份:2014作者:Pilar Sánchez-Blázquez; María Rodríguez-Muñoz; Raquel Herrero-Labrador; Javier Burgueño; Daniel Zamanillo; Javier Garzón