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药效评价Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering.

期刊:PloS one发表年份:2014作者:Scott Boitano; Justin Hoffman; Dipti V Tillu; Marina N Asiedu; Zhenyu Zhang; Cara L Sherwood; Yan Wang; Xinzhong Dong; Theodore J Price; Josef Vagner

药效评价SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C.

期刊:Neuropharmacology发表年份:2014作者:Sang-Min Lee; Andrew Kant; Daniel Blake; Vishakantha Murthy; Kevin Boyd; Steven J Wyrick; Richard B Mailman

药效评价Synthesis and evaluation of three structurally related ¹⁸F-labeled orvinols of different intrinsic activities: 6-O-[¹⁸F]fluoroethyl-diprenorphine ([¹⁸F]FDPN), 6-O-[¹⁸F]fluoroethyl-buprenorphine ([¹⁸F]FBPN), and 6-O-[¹⁸F]fluoroethyl-phenethyl-orvinol

期刊:Journal of medicinal chemistry发表年份:2014作者:Bent W Schoultz; Trine Hjørnevik; Brian J Reed; János Marton; Christopher S Coello; Frode Willoch; Gjermund Henriksen

药效评价Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes.

期刊:PloS one发表年份:2014作者:Christel Logez; Sylvie Berger; Céline Legros; Jean-Louis Banères; William Cohen; Philippe Delagrange; Olivier Nosjean; Jean A Boutin; Gilles Ferry; Frédéric Simonin; Renaud Wagner