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药效评价Antimalarial activities of 6-iodouridine and its prodrugs and potential for combination therapy.

期刊:Journal of medicinal chemistry发表年份:2013作者:Ian E Crandall; Ewa Wasilewski; Angelica M Bello; Asif Mohmmed; Pawan Malhotra; Emil F Pai; Kevin C Kain; Lakshmi P Kotra

药效评价Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283.

期刊:Journal of medicinal chemistry发表年份:2013作者:Peter Bach; Thomas Antonsson; Ruth Bylund; Jan-Arne Björkman; Krister Österlund; Fabrizio Giordanetto; J J J van Giezen; Søren M Andersen; Helen Zachrisson; Fredrik Zetterberg

药效评价Validation of a high-throughput, automated electrophysiology platform for the screening of nicotinic agonists and antagonists.

期刊:Journal of biomolecular screening发表年份:2013作者:John D Graef; Lisa C Benson; Serguei S Sidach; Haiyang Wei; Patrick M Lippiello; Merouane Bencherif; Nikolai B Fedorov

药效评价Dual-point competition association assay: a fast and high-throughput kinetic screening method for assessing ligand-receptor binding kinetics.

期刊:Journal of biomolecular screening发表年份:2013作者:Dong Guo; Erika J H van Dorp; Thea Mulder-Krieger; Jacobus P D van Veldhoven; Johannes Brussee; Adriaan P Ijzerman; Laura H Heitman