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基因编辑仓鼠The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor.

期刊:The Journal of biological chemistry发表年份:2012作者:Louise Valentin-Hansen; Marleen Groenen; Rie Nygaard; Thomas M Frimurer; Nicholas D Holliday; Thue W Schwartz

基因编辑仓鼠Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutants.

期刊:PloS one发表年份:2012作者:Yueming Zheng; Xuejing Zhu; Pingzheng Zhou; Xi Lan; Haiyan Xu; Min Li; Zhaobing Gao

基因编辑仓鼠Site of action of a pentapeptide agonist at the glucagon-like peptide-1 receptor. Insight into a small molecule agonist-binding pocket.

期刊:Bioorganic & medicinal chemistry letters发表年份:2012作者:Maoqing Dong; Delia I Pinon; Laurence J Miller

基因编辑仓鼠Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification.

期刊:Human molecular genetics发表年份:2012作者:Kristian Tveten; Øystein L Holla; Jamie Cameron; Thea Bismo Strøm; Knut Erik Berge; Jon K Laerdahl; Trond P Leren