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基因编辑仓鼠Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors.

期刊:Clinical cancer research : an official journal of the American Association for Cancer Research发表年份:2012作者:Michael C Heinrich; Diana Griffith; Arin McKinley; Janice Patterson; Ajia Presnell; Abhijit Ramachandran; Maria Debiec-Rychter

基因编辑仓鼠Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.

期刊:PloS one发表年份:2012作者:Nabil G Seidah; Steve Poirier; Maxime Denis; Rex Parker; Bowman Miao; Claudio Mapelli; Annik Prat; Hanny Wassef; Jean Davignon; Katherine A Hajjar; Gaétan Mayer

基因编辑仓鼠R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy.

期刊:Journal of the American College of Cardiology发表年份:2012作者:Stefan A Mann; Maria L Castro; Monique Ohanian; Guanglan Guo; Poonam Zodgekar; Angela Sheu; Kathryn Stockhammer; Tina Thompson; David Playford; Rajesh Subbiah; Dennis Kuchar; Anu Aggarwal; Jamie I Vandenberg; Diane Fatkin

基因编辑仓鼠The phosphocholine-binding pocket on C-reactive protein is necessary for initial protection of mice against pneumococcal infection.

期刊:The Journal of biological chemistry发表年份:2012作者:Toh B Gang; David J Hammond; Sanjay K Singh; Donald A Ferguson; Vinod K Mishra; Alok Agrawal