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药效评价A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.

期刊:Molecular pharmacology发表年份:2013作者:Matthew O Barrett; Juliana I Sesma; Christopher B Ball; P Suresh Jayasekara; Kenneth A Jacobson; Eduardo R Lazarowski; T Kendall Harden

药效评价Reverse engineering of the selective agonist TBPB unveils both orthosteric and allosteric modes of action at the M₁ muscarinic acetylcholine receptor.

期刊:Molecular pharmacology发表年份:2013作者:Peter Keov; Celine Valant; Shane M Devine; J Robert Lane; Peter J Scammells; Patrick M Sexton; Arthur Christopoulos

药效评价Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides.

期刊:The Journal of biological chemistry发表年份:2013作者:Jing He; W Berkeley Kauffman; Taylor Fuselier; Somanna K Naveen; Thomas G Voss; Kalina Hristova; William C Wimley

药效评价Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.

期刊:Molecular pharmacology发表年份:2013作者:J Robert Lane; Pavel Chubukov; Wei Liu; Meritxell Canals; Vadim Cherezov; Ruben Abagyan; Raymond C Stevens; Vsevolod Katritch