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药效评价Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases.

期刊:Bioorganic & medicinal chemistry发表年份:2013作者:David A Sandham; Nicola Arnold; Heinrich Aschauer; Kamlesh Bala; Lucy Barker; Lyndon Brown; Zarin Brown; David Budd; Brian Cox; Cerys Docx; Gerald Dubois; Nicholas Duggan; Karen England; Brian Everatt; Marcus Furegati; Edward Hall; Frank Kalthoff; An

药效评价Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.

期刊:The Journal of allergy and clinical immunology发表年份:2013作者:Donavan T Cheng; Cynthia Ma; Jens Niewoehner; Martin Dahl; Angela Tsai; Jun Zhang; Waldemar Gonsiorek; Subbu Apparsundaram; Achal Pashine; Palanikumar Ravindran; Jimmy Jung; Julie Hang; John Allard; Hans Bitter; Catherine Tribouley; Satwant Narula; S

药效评价Pharmacological profile of 2-bromoterguride at human dopamine D2, porcine serotonin 5-hydroxytryptamine 2A, and α2C-adrenergic receptors, and its antipsychotic-like effects in rats.

期刊:The Journal of pharmacology and experimental therapeutics发表年份:2013作者:F Jantschak; J Brosda; R T Franke; H Fink; D Möller; H Hübner; P Gmeiner; H H Pertz

药效评价Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments.

期刊:Cell calcium发表年份:2013作者:Yeranddy A Alpizar; Alicia Sanchez; Ahmed Radwan; Islam Radwan; Thomas Voets; Karel Talavera