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基因编辑仓鼠Absence of Genotoxic and Mutagenic Effects of Zingiber zerumbet (L.) Smith (Zingiberaceae) Extract.

期刊:Evidence-based complementary and alternative medicine : eCAM发表年份:2012作者:Chia Ju Chang; Thing-Fong Tzeng; Shorong-Shii Liou; Yuan-Shiun Chang; I-Min Liu

基因编辑仓鼠Discovery of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure-based design and in vivo reduction of amyloid β-peptides.

期刊:Journal of medicinal chemistry发表年份:2012作者:Heinrich Rueeger; Rainer Lueoend; Olivier Rogel; Jean-Michel Rondeau; Henrik Möbitz; Rainer Machauer; Laura Jacobson; Matthias Staufenbiel; Sandrine Desrayaud; Ulf Neumann

基因编辑仓鼠Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.

期刊:Investigational new drugs发表年份:2012作者:Timothy P Burkholder; Joshua R Clayton; Mark E Rempala; James R Henry; John M Knobeloch; David Mendel; Johnathan A McLean; Yan Hao; David A Barda; Eileen L Considine; Mark T Uhlik; Yuefeng Chen; Liandong Ma; Laura J Bloem; Jacqueline K Akunda; Denis

基因编辑仓鼠Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.

期刊:Molecular pharmacology发表年份:2012作者:Gyöngyi N Kiss; James I Fells; Renuka Gupte; Sue-Chin Lee; Jianxiong Liu; Nóra Nusser; Keng G Lim; Ramesh M Ray; Fang-Tsyr Lin; Abby L Parrill; Balázs Sümegi; Duane D Miller; Gabor Tigyi