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肿瘤模型Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody-Drug Conjugates.

期刊:Molecular cancer therapeutics发表年份:2015作者:Rémy Gébleux; Sarah Wulhfard; Giulio Casi; Dario Neri

肿瘤模型Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation.

期刊:The Journal of biological chemistry发表年份:2015作者:Cynthia Dayer; Ivan Stamenkovic

肿瘤模型The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity.

期刊:Oncotarget发表年份:2015作者:Yukinari Kato; Akiko Kunita; Shinji Abe; Satoshi Ogasawara; Yuki Fujii; Hiroharu Oki; Masashi Fukayama; Yasuhiko Nishioka; Mika K Kaneko

肿瘤模型Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface.

期刊:The Journal of biological chemistry发表年份:2015作者:Aiwen Dong; Dariusz Wodziak; Anson W Lowe