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肿瘤模型Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma.

期刊:Oncotarget发表年份:2015作者:Sang-Hyun Lee; In Cheul Jeung; Tae Woo Park; Kyungmin Lee; Dong Gwang Lee; Young-Lai Cho; Tae Sup Lee; Hee-Jun Na; Young-Jun Park; Hee Gu Lee; Mun Sik Jeong; Kwang-Hee Bae; Sang Chul Lee; Hyo Jin Lee; Young-Guen Kwon; Hyo Jeong Hong; Jang-Seong Kim;

肿瘤模型New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.

期刊:Molecular pharmacology发表年份:2015作者:Luca Gasparoli; Massimo D'Amico; Marika Masselli; Serena Pillozzi; Rachel Caves; Rawan Khuwaileh; Wolfgang Tiedke; Kenneth Mugridge; Alessandro Pratesi; John S Mitcheson; Giuseppe Basso; Andrea Becchetti; Annarosa Arcangeli

肿瘤模型Generation and characterization of a target-selectively activated antibody against epidermal growth factor receptor with enhanced anti-tumor potency.

期刊:mAbs发表年份:2015作者:Yun Yang; Qingcheng Guo; Mao Xia; Yantao Li; Xiaoyun Peng; Tao Liu; Xin Tong; Jin Xu; Huaizu Guo; Weizhu Qian; Sheng Hou; Jianxin Dai; Hao Wang; Rong Liu; Yajun Guo

肿瘤模型Novel glycosylated VEGF decoy receptor fusion protein, VEGF-Grab, efficiently suppresses tumor angiogenesis and progression.

期刊:Molecular cancer therapeutics发表年份:2015作者:Jung-Eun Lee; Chan Kim; Hannah Yang; Intae Park; Nuri Oh; Serenus Hua; Haneul Jeong; Hyun Joo An; Sun Chang Kim; Gyun Min Lee; Gou Young Koh; Ho Min Kim