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药效评价Rationally targeted, conformationally constrained, oxetane-modified oligonucleotides demonstrate efficient gene-silencing activity in a cellular system.

期刊:Annals of the New York Academy of Sciences发表年份:2005作者:J B Opalinska; A M Gewirtz

药效评价Preparation and characterization of calibration beads for sorting cells expressing a beta-lactamase gene reporter.

期刊:Cytometry. Part A : the journal of the International Society for Analytical Cytology发表年份:2005作者:Michael E Cunningham; Marianna Kapitskaya; Konstantin Petrukhin; Bohumil Bednar

药效评价Discovery of 2-aminothiazole-4-carboxamides, a novel class of muscarinic M(3) selective antagonists, through solution-phase parallel synthesis.

期刊:Chemical & pharmaceutical bulletin发表年份:2005作者:Yufu Sagara; Morihiro Mitsuya; Minaho Uchiyama; Yoshio Ogino; Toshifumi Kimura; Norikazu Ohtake; Toshiaki Mase

药效评价Discovery of the first potent, selective 5-hydroxytryptamine1D receptor antagonist.

期刊:Journal of medicinal chemistry发表年份:2005作者:Simon E Ward; Frank P Harrington; Laurie J Gordon; Susanna C Hopley; Claire M Scott; Jeannette M Watson