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药效评价Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets.

期刊：Pharmacology, biochemistry, and behavior发表年份：2012作者：Ruth A Duffy; Cynthia Morgan; Robert Naylor; Guy A Higgins; Geoffrey B Varty; Jean E Lachowicz; Eric M Parker
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药效评价S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.

期刊：Bioorganic & medicinal chemistry letters发表年份：2012作者：Ajit Shokar; Aaron Au; Seung Hwan An; Elsie Tong; Gabriel Garza; Jessica Zayas; Stanislaw F Wnuk; Kirkwood M Land
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药效评价Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor.

期刊：Bioorganic & medicinal chemistry letters发表年份：2012作者：James M Salovich; Paige N Vinson; Douglas J Sheffler; Atin Lamsal; Thomas J Utley; Anna L Blobaum; Thomas M Bridges; Uyen Le; Carrie K Jones; Michael R Wood; J Scott Daniels; P Jeffrey Conn; Colleen M Niswender; Craig W Lindsley; Corey R Hopkins
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药效评价Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists.

期刊：Journal of medicinal chemistry发表年份：2012作者：Xin Chen; Maria F Sassano; Lianyou Zheng; Vincent Setola; Meng Chen; Xu Bai; Stephen V Frye; William C Wetsel; Bryan L Roth; Jian Jin
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