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药效评价Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP.

期刊:Chemistry & biology发表年份:2012作者:Graeme W Carlile; Robert A Keyzers; Katrina A Teske; Renaud Robert; David E Williams; Roger G Linington; Christopher A Gray; Ryan M Centko; Luping Yan; Suzana M Anjos; Heidi M Sampson; Donglei Zhang; Jie Liao; John W Hanrahan; Raymond J Andersen; Dav

药效评价Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways.

期刊:Biochemical pharmacology发表年份:2012作者:R A Bilardi; K-I Kimura; D R Phillips; S M Cutts

药效评价Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening.

期刊:Journal of medicinal chemistry发表年份:2012作者:Dilip K Tosh; Khai Phan; Zhan-Guo Gao; Andrei A Gakh; Fei Xu; Francesca Deflorian; Ruben Abagyan; Raymond C Stevens; Kenneth A Jacobson; Vsevolod Katritch

药效评价Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site.

期刊:Molecular pharmacology发表年份:2012作者:Alexander J Donovan; Katherine Lansu; Jason G Williams; Mitchell F Denning; Saverio Gentile