郑州微飒生物科技有限责任公司 咨询热线:0371-88821766
行业动态

行业动态

追踪行业前沿,洞察产业趋势

药效评价The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1).

期刊:Biochimica et biophysica acta发表年份:2012作者:Eser J Zerenturk; Ika Kristiana; Saloni Gill; Andrew J Brown

药效评价Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling.

期刊:Molecular pharmacology发表年份:2012作者:Andrew C Emery; John O DiRaddo; Eric Miller; Hannah A Hathaway; Sergey Pshenichkin; Guy Rodrigue Takoudjou; Ewa Grajkowska; Robert P Yasuda; Barry B Wolfe; Jarda T Wroblewski

药效评价The inwardly rectifying potassium channel Kir1.1: development of functional assays to identify and characterize channel inhibitors.

期刊:Assay and drug development technologies发表年份:2012作者:John P Felix; Birgit T Priest; Kelli Solly; Timothy Bailey; Richard M Brochu; Chou J Liu; Martin G Kohler; Laszlo Kiss; Magdalena Alonso-Galicia; Haifeng Tang; Alexander Pasternak; Gregory J Kaczorowski; Maria L Garcia

药效评价δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.

期刊:The Journal of biological chemistry发表年份:2012作者:Miao Xu; Ke Liu; Manju Swaroop; Forbes D Porter; Rohini Sidhu; Sally Firnkes; Daniel S Ory; Juan J Marugan; Jingbo Xiao; Noel Southall; William J Pavan; Cristin Davidson; Steven U Walkley; Alan T Remaley; Ulrich Baxa; Wei Sun; John C McKew; Christoph