行业动态 - 郑州微飒生物科技有限责任公司

药效评价Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A₂A and A₃ adenosine receptor ligands.

期刊：Journal of medicinal chemistry发表年份：2012作者：Xiyan Hou; Mahesh S Majik; Kyunglim Kim; Yuna Pyee; Yoonji Lee; Varughese Alexander; Hwa-Jin Chung; Hyuk Woo Lee; Girish Chandra; Jin Hee Lee; Seul-Gi Park; Won Jun Choi; Hea Ok Kim; Khai Phan; Zhan-Guo Gao; Kenneth A Jacobson; Sun Choi; Sang Kook Le

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药效评价Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.

期刊：Psychopharmacology发表年份：2012作者：John P Redrobe; Lisbeth Elster; Kristen Frederiksen; Christoffer Bundgaard; Inge E M de Jong; Garrick P Smith; Anne Techau Bruun; Peter H Larsen; Michael Didriksen

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药效评价A TSHR-LH/CGR chimera that measures functional thyroid-stimulating autoantibodies (TSAb) can predict remission or recurrence in Graves' patients undergoing antithyroid drug (ATD) treatment.

期刊：The Journal of clinical endocrinology and metabolism发表年份：2012作者：Cesidio Giuliani; Dominique Cerrone; Norikazu Harii; Mark Thornton; Leonard D Kohn; Nilesh M Dagia; Ines Bucci; Maria Carpentieri; Barbara Di Nenno; Andrea Di Blasio; Paolo Vitti; Fabrizio Monaco; Giorgio Napolitano

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药效评价Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter.

期刊：The Journal of pharmacology and experimental therapeutics发表年份：2012作者：Alan Menter; Breck Thrash; Christina Cherian; Larry H Matherly; Lei Wang; Aleem Gangjee; Joel R Morgan; Dean Y Maeda; Aaron D Schuler; Stuart J Kahn; John A Zebala

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