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药效评价Identification of multiple 5-HT₄ partial agonist clinical candidates for the treatment of Alzheimer's disease.

期刊:Journal of medicinal chemistry发表年份:2012作者:Michael A Brodney; David E Johnson; Aarti Sawant-Basak; Karen J Coffman; Elena M Drummond; Emily L Hudson; Katherine E Fisher; Hirohide Noguchi; Nobuaki Waizumi; Laura L McDowell; Alexandros Papanikolaou; Betty A Pettersen; Anne W Schmidt; Elaine Tse

药效评价2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent transient receptor potential vanilloid 1 (TRPV1) antagonists: structure-activity relationships of 2-amino derivatives in the N-(6-trifluoromethylpyridin-3-ylmethyl) C-region.

期刊:Journal of medicinal chemistry发表年份:2012作者:Myeong Seop Kim; HyungChul Ryu; Dong Wook Kang; Seong-Hee Cho; Sejin Seo; Young Soo Park; Mi-Yeon Kim; Eun Joo Kwak; Yong Soo Kim; Rahul S Bhondwe; Ho Shin Kim; Seul-gi Park; Karam Son; Sun Choi; Ian A DeAndrea-Lazarus; Larry V Pearce; Peter M Blumbe

药效评价Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism.

期刊:British journal of pharmacology发表年份:2012作者:Nicolette C Ross; Kate J Reilley; Thomas F Murray; Jane V Aldrich; Jay P McLaughlin

药效评价Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury.

期刊:Neuroscience发表年份:2012作者:P W Brownjohn; J C Ashton